Gene cascades and homeotic genes

MabbittN · 31 Oct 2004, 6:30 PM

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Can anyone explain the process of gene cascades and homeotic genes?
Thanks.

Tommy_Lamp · 31 Oct 2004, 7:45 PM

Gene cascades: In birds and mammals, many genes control the development of genes. AS one gene is turned on, it releases transcription factor which in turn switch on another gene. That is, the products of many genes control the expression of others. This occues in a cascade of signals.
Homeotic Genes: Are important transcription factor genes which control the development of most organ systems.

neo o · 21 Nov 2004, 7:53 PM

Homologue/homeotic genes are similar DNA sequences found in different organisms. These include homeobox genes which have been found in a wide range of organisms. Since similar homeobox genes have been found in every eukaryote studied from fruit flies to humans, and the fact that they retain similar functioning in these organisms has lead scientists to the conclusion that they are further evidence of evolutionary relationships between organisms.

For cascades :

•Pattern formation (development of parts of body) is not controlled by a single gene - many genes need to be switched on or off in the appropriate sequence to form the various structures of the body e.g. limbs
•A gene cascade occurs as the action of each gene causes the next gene(s) to be turned on, like in limb development.
•As each gene is turned on, substances that turn on the next gene(s) are produced, called transcription factors. The expression of 1 gene can turn on multiple genes through the production of >1 protein.
•Vertebrate limbs begin as undifferentiated limb buds that give rise to their unique forms.
•Certain molecules induce the formation of a zone that secretes the sonic hedgehog factor, inducing nearby cells to form posterior structures such as limbs.

Hrm, I just realised how old this thread is, and how useless my reply is lol

Whimsical_Fairy · 7 Sep 2006, 2:49 PM

Not That Useless!!
Thx

ditto · 7 Sep 2006, 4:21 PM

that's true! i was just doin a paper yesterday and there was a q about 'gene cascade' and this just helped me! cool!

hla_khine2002 · 30 Aug 2009, 1:49 PM

Thanks mate, that was helpful. i appreciate your help.

clarebear14 · 27 Oct 2009, 6:13 PM

thnx

31 Oct 2004, 6:30 PM	#1 (permalink)
MabbittN New Member Join Date: May 2004 Posts: 3 Last Activity: 18 Mar 2005, 10:54 PM	Gene cascades and homeotic genes You can hide this advertisement by registering. Can anyone explain the process of gene cascades and homeotic genes? Thanks.

31 Oct 2004, 7:45 PM	#2 (permalink)
Tommy_Lamp Coco HSC: 2004 Gender: Undisclosed Location: Northern Beaches Join Date: Jun 2004 Posts: 1,748 Last Activity: 1 Dec 2006, 11:48 AM	Gene cascades: In birds and mammals, many genes control the development of genes. AS one gene is turned on, it releases transcription factor which in turn switch on another gene. That is, the products of many genes control the expression of others. This occues in a cascade of signals. Homeotic Genes: Are important transcription factor genes which control the development of most organ systems. __________________

21 Nov 2004, 7:53 PM	#3 (permalink)
neo o it's coming to me... HSC: 2004 Gender: Male Join Date: Aug 2002 Posts: 3,365 Last Activity: 27 Aug 2009, 2:29 PM	Homologue/homeotic genes are similar DNA sequences found in different organisms. These include homeobox genes which have been found in a wide range of organisms. Since similar homeobox genes have been found in every eukaryote studied from fruit flies to humans, and the fact that they retain similar functioning in these organisms has lead scientists to the conclusion that they are further evidence of evolutionary relationships between organisms. For cascades : •Pattern formation (development of parts of body) is not controlled by a single gene - many genes need to be switched on or off in the appropriate sequence to form the various structures of the body e.g. limbs •A gene cascade occurs as the action of each gene causes the next gene(s) to be turned on, like in limb development. •As each gene is turned on, substances that turn on the next gene(s) are produced, called transcription factors. The expression of 1 gene can turn on multiple genes through the production of >1 protein. •Vertebrate limbs begin as undifferentiated limb buds that give rise to their unique forms. •Certain molecules induce the formation of a zone that secretes the sonic hedgehog factor, inducing nearby cells to form posterior structures such as limbs. Hrm, I just realised how old this thread is, and how useless my reply is lol __________________ Law ANU (5th year, Hons)

7 Sep 2006, 2:49 PM	#4 (permalink)
Whimsical_Fairy New Member HSC: 2006 Gender: Female Join Date: Jan 2006 Posts: 6 Last Activity: 23 Dec 2008, 5:03 PM	Re: Gene cascades and homeotic genes Not That Useless!! Thx

7 Sep 2006, 4:21 PM	#5 (permalink)
ditto drops of jupiter HSC: 2006 Gender: Female Location: still searching for Captain Planet Join Date: Jan 2006 Posts: 123 Last Activity: 17 Nov 2009, 12:54 PM	Re: Gene cascades and homeotic genes that's true! i was just doin a paper yesterday and there was a q about 'gene cascade' and this just helped me! cool!

30 Aug 2009, 1:49 PM	#6 (permalink)
hla_khine2002 New Member HSC: N/A Gender: Male Join Date: Aug 2009 Posts: 1 Last Activity: 8 Nov 2009, 2:10 AM	Re: Gene cascades and homeotic genes Thanks mate, that was helpful. i appreciate your help.

27 Oct 2009, 6:13 PM	#7 (permalink)
clarebear14 New Member HSC: 2009 Gender: Female Join Date: Nov 2008 Posts: 5 Last Activity: 12 Nov 2009, 11:26 PM	Re: Gene cascades and homeotic genes thnx

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