Genetics Challenge Question

**Survivor39** · 9 Jul 2005, 4:28 PM

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I am not sure if this is a good question or not, but for those of you who did the genetics option, or even the genetic topics, would have learned how the process of cloning works.

In the cloning of Dolly, one of the step invovles the extraction of udder cells from Sheep 1. These cells are important because the genome is going to be inserted into an egg from Sheep No. 2.

Scientist starve these udder cells (I'm not sure how, probably inoculate them into a nutrient limited broth). Why do you think this was done?

currysauce · 9 Jul 2005, 4:36 PM

So the cell doesn't start dividing????? The tissue culture medium is adjusted to starve cells and maintain them in the G zero stage of the cell cycle. During the G zero phase, the cell, viewed from this perspective, lives through a completely "altruistic" phase.

It can still survive... i think...

The G phase is shown in this picture...

acmilan · 9 Jul 2005, 4:44 PM

From memory, nutrient deprivation interrupted the normal growth and division cycle of a cell, thus allowing them to 'reprogram' it with the new nucleus

**Survivor39** · 9 Jul 2005, 4:55 PM

While you're still answering the first question, I've got another interesting, not necessarily "challenging", for you.

In one of your option textbook for genetics, the author wrote about the Human Genone Project:
"Because chromosomes occur in homologues, identical pairs, it is only necessry to sequence 24 chromosomes, that is, the X and Y, and one member of each of the other 22 pairs"

Do you see some minor error with this sentence?

currysauce · 9 Jul 2005, 4:59 PM

no clue, how'd i go on the first quesiton LOL

**Survivor39** · 9 Jul 2005, 5:01 PM

I'll PM you so it won't spoil the chance from everyone having ago.

malkin86 · 12 Jul 2005, 4:30 PM

Quote:

Originally Posted by Survivor39

While you're still answering the first question, I've got another interesting, not necessarily "challenging", for you.

In one of your option textbook for genetics, the author wrote about the Human Genone Project:
"Because chromosomes occur in homologues, identical pairs, it is only necessry to sequence 24 chromosomes, that is, the X and Y, and one member of each of the other 22 pairs"

Do you see some minor error with this sentence?

22 pairs and one X and one Y chromosome doesn't = 24 chromosomes, it equals 46.

**Survivor39** · 12 Jul 2005, 4:38 PM

No that's not it.
The author meant that you need to sequence 1 chromosome from each homologous autosomal pair (44/2 = 22 chromosomes), then sequence both sex chromosomes (2). Giving 24 chromosome sequences.

k_stroud22 · 5 Aug 2006, 1:48 PM

Sorry, i have no idea....maybe 'homologues' is spelt wrong? *hides under the chair for her ignornace...*

simplistic · 18 Oct 2006, 9:13 PM

so there is no error ?
because the homologous r the same so u need one of each 22
but the x and y r diff so u need both therefor ull need 24

simplistic · 18 Oct 2006, 9:16 PM

hey can u post all the answers to the questions soon like b4 the bio hsc the questions r reallly brain boosters lol

**Survivor39** · 18 Oct 2006, 9:24 PM

Answer:

Are both copy of your chromosomes really identical? No. You could be heterozygous at cetrain loci. Then, therefore, your homologues are not completely identical.

simplistic · 18 Oct 2006, 9:33 PM

crossing over ?

Dr_Doom · 5 Nov 2006, 2:56 PM

Is the answer to the first question because if the enoculated egg doesn't have any cells inside of it, it will lyse. But if the activity is temporarily inhibited, it will preserve the egg until it is needed....?

9 Jul 2005, 4:28 PM	#1 (permalink)
Survivor39 Moderator HSC: 2003 Gender: Undisclosed Join Date: May 2003 Posts: 4,205 Last Activity: Today, 11:04 AM	Genetics Challenge Question You can hide this advertisement by registering. I am not sure if this is a good question or not, but for those of you who did the genetics option, or even the genetic topics, would have learned how the process of cloning works. In the cloning of Dolly, one of the step invovles the extraction of udder cells from Sheep 1. These cells are important because the genome is going to be inserted into an egg from Sheep No. 2. Scientist starve these udder cells (I'm not sure how, probably inoculate them into a nutrient limited broth). Why do you think this was done? __________________ PhD, University of Cambridge, 09-12 MSc, UNSW, 08-09 BMedSc (Hons I), UNSW, 04-07

9 Jul 2005, 4:36 PM	#2 (permalink)
currysauce Actuary in the making HSC: 2005 Gender: Male Location: Glenmore Park - its so confusing Join Date: Aug 2004 Posts: 571 Last Activity: 4 Nov 2009, 6:40 PM	So the cell doesn't start dividing????? The tissue culture medium is adjusted to starve cells and maintain them in the G zero stage of the cell cycle. During the G zero phase, the cell, viewed from this perspective, lives through a completely "altruistic" phase. It can still survive... i think... The G phase is shown in this picture... __________________ Class of '05 UAI: 97.60 Commerce (Actuarial Studies) /Science(Mathematics & Statistics) @ UNSW Last edited by currysauce; 9 Jul 2005 at 4:52 PM.

9 Jul 2005, 4:55 PM	#4 (permalink)
Survivor39 Moderator HSC: 2003 Gender: Undisclosed Join Date: May 2003 Posts: 4,205 Last Activity: Today, 11:04 AM	While you're still answering the first question, I've got another interesting, not necessarily "challenging", for you. In one of your option textbook for genetics, the author wrote about the Human Genone Project: "Because chromosomes occur in homologues, identical pairs, it is only necessry to sequence 24 chromosomes, that is, the X and Y, and one member of each of the other 22 pairs" Do you see some minor error with this sentence? __________________ PhD, University of Cambridge, 09-12 MSc, UNSW, 08-09 BMedSc (Hons I), UNSW, 04-07

9 Jul 2005, 4:59 PM	#5 (permalink)
currysauce Actuary in the making HSC: 2005 Gender: Male Location: Glenmore Park - its so confusing Join Date: Aug 2004 Posts: 571 Last Activity: 4 Nov 2009, 6:40 PM	no clue, how'd i go on the first quesiton LOL __________________ Class of '05 UAI: 97.60 Commerce (Actuarial Studies) /Science(Mathematics & Statistics) @ UNSW

9 Jul 2005, 5:01 PM	#6 (permalink)
Survivor39 Moderator HSC: 2003 Gender: Undisclosed Join Date: May 2003 Posts: 4,205 Last Activity: Today, 11:04 AM	I'll PM you so it won't spoil the chance from everyone having ago. __________________ PhD, University of Cambridge, 09-12 MSc, UNSW, 08-09 BMedSc (Hons I), UNSW, 04-07

9 Jul 2005, 4:44 PM	#3 (permalink)
acmilan I'll stab ya HSC: N/A Gender: Male Location: Jumanji Join Date: May 2004 Posts: 3,884 Last Activity: 15 Nov 2009, 6:03 PM	From memory, nutrient deprivation interrupted the normal growth and division cycle of a cell, thus allowing them to 'reprogram' it with the new nucleus

12 Jul 2005, 4:38 PM	#8 (permalink)
Survivor39 Moderator HSC: 2003 Gender: Undisclosed Join Date: May 2003 Posts: 4,205 Last Activity: Today, 11:04 AM	No that's not it. The author meant that you need to sequence 1 chromosome from each homologous autosomal pair (44/2 = 22 chromosomes), then sequence both sex chromosomes (2). Giving 24 chromosome sequences. __________________ PhD, University of Cambridge, 09-12 MSc, UNSW, 08-09 BMedSc (Hons I), UNSW, 04-07

5 Aug 2006, 1:48 PM	#9 (permalink)
k_stroud22 UAI 2006 83.70 HSC: 2006 Gender: Female Location: Coffs Harbour Join Date: Dec 2005 Posts: 66 Last Activity: 10 Nov 2008, 8:06 PM	Re: Genetics Challenge Question Sorry, i have no idea....maybe 'homologues' is spelt wrong? hides under the chair for her ignornace...

18 Oct 2006, 9:13 PM	#10 (permalink)
simplistic nice as ice HSC: 2007 Gender: Female Location: somewhere away from you Join Date: Aug 2006 Posts: 211 Last Activity: 30 Mar 2008, 4:04 PM	Re: Genetics Challenge Question so there is no error ? because the homologous r the same so u need one of each 22 but the x and y r diff so u need both therefor ull need 24

18 Oct 2006, 9:16 PM	#11 (permalink)
simplistic nice as ice HSC: 2007 Gender: Female Location: somewhere away from you Join Date: Aug 2006 Posts: 211 Last Activity: 30 Mar 2008, 4:04 PM	Re: Genetics Challenge Question hey can u post all the answers to the questions soon like b4 the bio hsc the questions r reallly brain boosters lol

18 Oct 2006, 9:24 PM	#12 (permalink)
Survivor39 Moderator HSC: 2003 Gender: Undisclosed Join Date: May 2003 Posts: 4,205 Last Activity: Today, 11:04 AM	Re: Genetics Challenge Question Answer: Are both copy of your chromosomes really identical? No. You could be heterozygous at cetrain loci. Then, therefore, your homologues are not completely identical. __________________ PhD, University of Cambridge, 09-12 MSc, UNSW, 08-09 BMedSc (Hons I), UNSW, 04-07

18 Oct 2006, 9:33 PM	#13 (permalink)
simplistic nice as ice HSC: 2007 Gender: Female Location: somewhere away from you Join Date: Aug 2006 Posts: 211 Last Activity: 30 Mar 2008, 4:04 PM	Re: Genetics Challenge Question crossing over ?

5 Nov 2006, 2:56 PM	#14 (permalink)
Dr_Doom Supreme Member HSC: 2006 Gender: Male Location: NSW Join Date: Oct 2005 Posts: 1,276 Last Activity: 25 Aug 2009, 4:56 PM	Re: Genetics Challenge Question Is the answer to the first question because if the enoculated egg doesn't have any cells inside of it, it will lyse. But if the activity is temporarily inhibited, it will preserve the egg until it is needed....?

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