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The Creatine Supplement Debate (1 Viewer)

hYperTrOphY

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Drink lots of water afterwards, im talking more than 1.5 litres, and have a banana before you go to bed that night. This will help in the re-building (ie. growth) of the muscles.
DO NOT have a banana after you workout! Fructose is no good after weight training. You want plenty of water, with dextrose, maltodextrin and sodium.

Some supplements I recommend are weigh protean powder. Theoretically you should be having it instead of meals, but thats really only subtable if you work out like, 5 times a week or more. I find it good just to have before bed after you've had a work out. Drink too much without the apropriate amuont of exercise and you will get protean pimples on your arms, which scar.
WTF are you talking about?? Protein powder should not be used to have "instead of meals". It is a supplement. It is designed to supplement a solid diet. If you are weight training you need quite a lot of protein - approx 3g per kilogram of bodyweight everyday. Protein powder is used to ensure you are getting enough, its not to drink every meal! Your protein sources should mostly come from whole foods such as chicken breast, steak and tuna. Also, I would like to see some scientific evidence of this reaction you call "protein pimples"??

Another one you can try is Creatin Monohydrate. Be careful with this, again, if you are not working out more than 5 times a week, you would only take it before a workout. I have a few friends who can't take it because their body seems to have a disagreement with it.
Creatine is an excellent supplement for those who go to the gym, and wish to gain mass. Once again, I'm not sure where you get your information... but it's wrong. When you start supplementing with creatine, you must load, which means taking about 20-25g per day (broken into 4-5 5g servings) for about a week. Then, you take 5g in the morning and 5g after you workout.
Your friend's body has a "disagreement with it" does it? Quite strange since creatine is found naturally in the body, and in the food we eat!
 

Cab31

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hYperTrOphY said:
DO NOT have a banana after you workout! Fructose is no good after weight training. You want plenty of water, with dextrose, maltodextrin and sodium.



WTF are you talking about?? Protein powder should not be used to have "instead of meals". It is a supplement. It is designed to supplement a solid diet. If you are weight training you need quite a lot of protein - approx 3g per kilogram of bodyweight everyday. Protein powder is used to ensure you are getting enough, its not to drink every meal! Your protein sources should mostly come from whole foods such as chicken breast, steak and tuna. Also, I would like to see some scientific evidence of this reaction you call "protein pimples"??



Creatine is an excellent supplement for those who go to the gym, and wish to gain mass. Once again, I'm not sure where you get your information... but it's wrong. When you start supplementing with creatine, you must load, which means taking about 20-25g per day (broken into 4-5 5g servings) for about a week. Then, you take 5g in the morning and 5g after you workout.
Your friend's body has a "disagreement with it" does it? Quite strange since creatine is found naturally in the body, and in the food we eat!
The long term effects of Creatine (supplimentation) are yet to be known. Its linked with heart problems, and the key principle behind the 'mass' that you gain is that the muscle gets bigger because it takes in more water. The more water present in the muscle, the lesser the performance inhibiting effects of Lactic acid (because it can be 'flushed out' with greater ease). This is why proffessional sports people use the suppliment. It doesnt make you stronger - but it will make your muscles bigger and aid in anaerobic events.
Please dont start typing in misleading information about taking doses of this suppliment - as i said the effects are relatively unknown - but they are linked with heart disease. There are people that dont know any better than to beleive that information that you posted and i would hate to think that they are doing themselves some damage by it.
 

Cab31

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hYperTrOphY said:
Those dosages are correct, and I can support whatever I say with hundreds of references if you wish?

I didnt mean that the information was incorrect. I meant that taking this suppliment is suspected to induce heart failure. There is 'free creatine' that is naturally found in the heart - as oposed to creatine-phosphate found in muscles. While the muscles can deal with the additional creatine suppliments, some scientists have suggested that the heart can not. And when Supplimentation ceases, there are adverse heart problems. Again i am not trying to tell you you are wrong. I am just telling everyone to be careful.
 
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mr_speedy

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i think its stupid for a begginer to take a suplement like creatine..... the have to start using weights first, get used to it all and everything. then once they become accustomed to it, start researching.

also creatine is not good on the kidneys... have to drink a lot of water when taking it...
 

Cab31

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Exactly. It really concerns me that there are people out there taking these suppliments when they:
(a) Don't understand what they do
(b) Don't understand the doses
(c) Don't need to take the suppliments as they are beginners

thanks mr speedy for summing that up :)
 

hYperTrOphY

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Here is an extract from "Creatine: A Meta Analysis" by Joe 'Yu Yevon" King

Safety of Creatine Supplementation

This subject is of utmost importance to athletes supplementing with creatine. It is important to note that the safety of creatine has been constantly skewed by the media who is ignorant of creatine’s effects on the human body. The effectiveness and relative safety of creatine is dependent on water intake. While supplementing with creatine, an athlete should drink water constantly throughout the day to improve its effectiveness and to stave off possible ill-effects such as nausea, stomach cramps and dehydration. With proper water intake, these symptoms will be eliminated.

More significantly, creatine is being used to treat disease. Major achievements made over the last several years have highlighted the important roles of creatine and the creatine kinase reaction in health and disease. Wyss (2002) investigated creatine’s effects on certain diseases and concluded that oral creatine supplementation improved the clinical symptoms in both AGAT and GAMT deficiency, which cause mental retardation. In addition, creatine supplementation displayed neuroprotective effects in several animal models of neurological disease, such as Huntington's disease, Parkinson's disease, and amyotrophic lateral sclerosis. All these findings pinpoint to a close correlation between the functional capacity of the creatine kinase/phosphorylcreatine/creatine system and proper brain function. They also offer a starting-point for novel means of delaying neurodegenerative disease, and for strengthening memory function and intellectual capabilities. Finally, creatine biosynthesis has been postulated as a major effecter of homocysteine concentration in the plasma, which has been identified as an independent graded risk factor for atherosclerotic disease. By decreasing homocysteine production, oral creatine supplementation may, thus, also lower the risk for developing coronary heart disease or cerebrovascular disease.

Taes et al. (2003) investigated the claim that creatine damages the kidneys. Taes and colleagues investigated the effect of prolonged creatine ingestion on renal function in animals with normal kidney function or pre-existing kidney failure. Results indicate that no detrimental effects of creatine supplementation on the renal function were observed. No differences were observed in insulin or creatinine clearance rates. Serum creatine and intramuscular total creatine concentrations were higher in creatine-supplemented groups. Creatine supplementation at a dosage of 2% w/w for 4 weeks does not impair kidney function in animals with pre-existing renal failure or in control animals.

These results agreed with Farquhar (2002) who stated, “despite relatively few isolated reports of renal dysfunction in persons taking creatine, the studies completed to date suggest that in normal healthy individuals the kidneys are able to excrete creatine, and its end product creatinine, in a manner that does not adversely alter renal function.”

Brudnak (2004) states that negative reports have been made of possible side effects of creatine supplementation, such as muscle cramping during exercise, and potential impurities. These effects can be minimized or eliminated entirely with proper water intake.
Also......

Long-Term Effects of Creatine

Many ignorant critics of creatine are quick to suggest that there are no long-term studies conducted on creatine supplementation and use this straw man fallacy to state that long-term creatine supplementation is not safe. In fact, there are many long term studies on creatine that have been conducted, all with positive endorsements for its use.

Mayhew et al. (2002) investigated creatine’s long-term effects on liver and kidney function. Twenty-three members of an NCAA Division II American football with at least two years of strength training experience were divided into a creatine monohydrate group in which they voluntarily and spontaneously ingested creatine, and a control in which they took no supplements. Individuals in the creatine monohydrate group averaged regular daily consumption of 5 to 20 g for 0.25 to 5.6 years. Venous blood analysis for serum albumin, alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, bilirubin, urea, and creatinine produced no significant differences between groups. Creatinine clearance was estimated from serum creatinine and was not significantly different between groups. Within the creatine monohydrate group, correlations between all blood parameters and either daily dosage or duration of supplementation were nont significant. Therefore, it appears that oral supplementation with creatine monohydrate has no long-term detrimental effects on kidney or liver functions in highly trained college athletes in the absence of other nutritional supplements.

Derave et al. (2003) studied creatine’s long-term efficiency. Recent findings in healthy humans indicate that the beneficial effect on muscle function and muscle total creatine content may disappear when creatine is continuously ingested for more than two or three months. The mechanism for this habituation to chronic creatine exposure is poorly understood and subsequently unverified.

Kreider et al. (2003) states that long-term creatine supplementation does not significantly affect clinical markers of health in athletes. This study examined the effects of long-term creatine supplementation on a 69-item panel of serum, whole blood, and urinary markers of clinical health status in athletes. Over a 21-month period, 98 Division IA college football players were administered in an open label manner creatine or non-creatine containing supplements following training sessions. Subjects who ingested creatine were administered 15.75 g/day of creatine monohydrate for 5 days and an average of 5 g/day thereafter in 5-10 g/day doses. Fasting blood and 24-h urine samples were collected at 0, 1, 1.5, 4, 6, 10, 12, 17, and 21 months of training. A comprehensive quantitative clinical chemistry panel was determined on serum and whole blood samples (metabolic markers, muscle and liver enzymes, electrolytes, lipid profiles, hematological markers, and lymphocytes). In addition, urine samples were quantitatively and qualitative analyzed to assess clinical status and renal function. Results revealed no significant differences among groups in the 54-item panel of quantitative blood and urine markers assessed. Univariate analysis revealed no clinically significant interactions among groups in markers of clinical status. In addition, no apparent differences were observed among groups in the 15-item panel of qualitative urine markers. Results indicate that long-term creatine supplementation (up to 21-months) does not appear to adversely effect markers of health status in athletes undergoing intense training in comparison to athletes who do not take creatine.

Schroder et al. (2004) used 18 professional basketball players of the first Spanish Basketball League. The participants ingested 5g of creatine monohydrate daily during three competition seasons. Blood was collected in the morning after an overnight fast, five times during each of the three official competition seasons. The results indicate that long-term (3-years) creatine monohydrate supplementation does not produce measurable abnormalities within the 16 clinical tests performed on the athletes.

It has been shown time and time again that there are no long-term adverse effects of creatine supplementation.
 
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hYperTrOphY

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Without Wings said:
and here's an extract from: Creatine Supplementation in Athletes: Review
by Mark A. Jenkins, MD




you can find both sides to the argument...

also in regards to dosages:

the dosage depends on your body weight, and whether you are in the load phase or the maintenance phase.

a one-size-fits-all sort of dosage regimen is incorrect
The extract I provided shows that a long term study HAS infact been undertaken!
The other 'side effects' outlined as possibilities in your article ARE acknowledged, but as explained, are easily avoided, as long as you have adequate water intake.

Here is the resource list for the article I presented:

Ajc, Z. Wakiewicze and W. Pilis. 2001: Anaerobic Power, Creatine Kinase Activity, Lactate Concentration, and Acid-Base Equilibrium Changes Following Bouts of Exhaustive Strength Exercises. The Journal of Strength and Conditioning Research: Vol. 15, No. 3, pp. 357–361.

Almada A, Kreider R, Ferreira M, Wilson M, Grindstaff P, Plisk S, Reinhardy J, Cantler E. Effects of calcium ß-HMB supplementation with or without creatine during training on strength and sprint capacity. FASEB J 1997

Almada A, Mitchell T, Earnest C. Impact of chronic creatine supplementation on serum enzyme concentrations. FASEB J 1996



Andrews R, Greenhaff P, Curtis S, Perry A, Cowley AJ. The effect of creatine supplementation on skeletal muscle metabolism in congestive heart failure. Eur Heart J. 1998.



Antonio PhD, CSCS. 2004: Creatine Loading and Maintenance Dosing. Strength and Conditioning Journal: Vol. 26, No. 1, pp. 26–27.



Arciero PJ, Hannibal NS 3rd, Nindl BC, Gentile CL, Hamed J, Vukovich MD. Comparison of creatine ingestion and resistance training on energy expenditure and limb blood flow. Metabolism. 2001 Dec;50(12):1429-34.



Archer MC. Creatine: a safety concern. Toxicol Lett. 2004 Sep 25;152(3):275.



Archer MC. The use of creatine to enhance athletic performance. Nutrition. 2004 Sep;20(9):841.



Arias A, Garcia-Villoria J, Ribes A. Guanidinoacetate and creatine/creatinine levels in controls and patients with urea cycle defects. Mol Genet Metab. 2004 Jul;82(3):220-3.



Arias-Mendoza F, Konchanin LM, Grover WD, Salganicoff L, Selak MA, Brown TR. Possible creatine synthesis deficit studied by in vivo magnetic resonance spectroscopy. Med Sci Sports Exerc. 1998.



Ayoama R, Hiruma E, Sasaki H. Effects of creatine loading on muscular strength and endurance of female softball players. J Sports Med Phys Fitness. 2003 Dec;43(4):481-7.



Balsom P, Ekblom B, Sjodin B, Hultman E. Creatine supplementation and dynamic high-intensity intermittent exercise. Scand J Med Sci Sport 1993;3:143-9.



Balsom P, Harridge S, Söderlund K, Sjodin B, Ekblom B. Creatine supplementation per se does not enhance endurance exercise performance. Acta Physiol Scand 1993;149:521-3.



Balsom P, Söderlund K, Ekblom B. Creatine in humans with special references to creatine supplementation. Sports Med 1994;18:268-80.



Balsom P, Söderlund K, Sjödin B, Ekblom B. Skeletal muscle metabolism during short duration high-intensity exercise: influence of creatine supplementation. Acta Physiol Scand 1995;1154:303-10.



Barnett C, Hinds M, Jenkins D. Effects of oral creatine supplementation on multiple sprint cycle performance. Aust J Sci Med. Sport 1996;28:35-9.



Becque B, Lochmann J, Melrose D. Effect of creatine supplementation during strength training on 1 RM and body composition. Med Sci Sport Exerc 1997;29:S146.



Bennett T, Bathalon G, Armstrong D 3rd, Martin B, Coll R, Beck R, Barkdull T, O'Brien K, Deuster PA. Effect of creatine on performance of militarily relevant tasks and soldier health. Mil Med. 2001 Nov;166(11):996-1002.



Bessman S, Savabi F. The role of the phosphocreatine energy shuttle in exercise and muscle hypertrophy. In: Taylor A, Gollnick P, Green H editors. International Series on Sport Sciences: Biochemistry of Exercise VII: Champaign, IL: Human Kinetics, 1988:167-78.



Birch R, Noble D, Greenhaff P. The influence of dietary creatine supplementation on performance during repeated bouts of maximal isokinetic cycling in man. Eur J Appl Physiol 1994;69:268-70.



Biwer CJ, Jensen RL, Schmidt WD, Watts PB. The effect of creatine on treadmill running with high-intensity intervals. J Strength Cond Res. 2003 Aug;17(3):439-45.



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Branch JD. Effect of creatine supplementation on body composition and performance: a meta-analysis. Int J Sport Nutr Exerc Metab. 2003 Jun;13(2):198-226.



Brault JJ, Terjung RL. Creatine uptake and creatine transporter expression among rat skeletal muscle fiber types. Am J Physiol Cell Physiol. 2003 Jun;284(6):C1481-9. Epub 2003 Feb 05.



Brault JJ, Abraham KA, Terjung RL. Muscle creatine uptake and creatine transporter expression in response to creatine supplementation and depletion. J Appl Physiol. 2003 Jun;94(6):2173-80. Epub 2003 Feb 28.



Brenner, J. Walberg Rankin and D. Sebolt. 2000: The Effect of Creatine Supplementation During Resistance Training in Women. The Journal of Strength and Conditioning Research: Vol. 14, No. 2, pp. 207–213.



Brewster LM, van Montfrans GA. Blood pressure, resting energy expenditure, and creatine kinase activity. Hypertension. 2004 Sep;44(3).



Brilla LR, Giroux MS, Taylor A, Knutzen KM. Magnesium-creatine supplementation effects on body water. Metabolism. 2003 Sep;52(9):1136-40.



Brose A, Parise G, Tarnopolsky MA. Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults. J Gerontol A Biol Sci Med Sci. 2003 Jan;58(1):11-9.



Brudnak MA. Creatine: are the benefits worth the risk? Toxicol Lett. 2004 Apr 15;150(1):123-30.



Burbaeva GSh, Savushkina OK, Boksha IS. Creatine kinase BB in brain in schizophrenia. World J Biol Psychiatry. 2003 Oct;4(4):177-83.



Burke DG, Chilibeck PD, Parise G, Candow DG, Mahoney D, Tarnopolsky M. Effect of creatine and weight training on muscle creatine and performance in vegetarians. Med Sci Sports Exerc. 2003 Nov;35(11):1946-55.



Burke, T. Smith-Palmer, L. E. Holt, B. Head and P. D. Chilibeck. 2001: The Effect of 7 Days of Creatine Supplementation on 24-Hour Urinary Creatine Excretion. The Journal of Strength and Conditioning Research: Vol. 15, No. 1, pp. 59–62.



Candow DG, Chilibeck PD, Chad KE, Chrusch MJ, Davison KS, Burke DG. Effect of ceasing creatine supplementation while maintaining resistance training in older men. J Aging Phys Act. 2004 Jul;12(3):219-31.



Ceddia RB, Sweeney G. Creatine supplementation increases glucose oxidation and AMPK phosphorylation and reduces lactate production in L6 rat skeletal muscle cells. J Physiol. 2004 Mar 1;555(Pt 2):409-21. Epub 2004 Jan 14.



Chang CT, Wu CH, Yang CW, Huang JY, Wu MS. Creatine monohydrate treatment alleviates muscle cramps associated with haemodialysis. Nephrol Dial Transplant. 2002 Nov;17(11):1978-81.



Christophe Delecluse, Rudi Diels and Marina Goris. 2003: Effect of Creatine Supplementation on Intermittent Sprint Running Performance in Highly Trained Athletes. The Journal of Strength and Conditioning Research: Vol. 17, No. 3, pp. 446–454.



Chrusch MJ, Chilibeck PD, Chad KE, Davison KS, Burke DG. Creatine supplementation combined with resistance training in older men. Med Sci Sports Exerc. 2001 Dec;33(12):2111-7.



Chwalbinska-Moneta J. Effect of creatine supplementation on aerobic performance and anaerobic capacity in elite rowers in the course of endurance training. Int J Sport Nutr Exerc Metab. 2003 Jun;13(2):173-83.



Cornelio AR, Rodrigues V Jr, de Souza Wyse AT, Dutra-Filho CS, Wajner M, Wannmacher CM. Tryptophan reduces creatine kinase activity in the brain cortex of rats. Int J Dev Neurosci. 2004 Apr;22(2):95-101.



Cottrell GT, Coast JR, Herb RA. Effect of recovery interval on multiple-bout sprint cycling performance after acute creatine supplementation. J Strength Cond Res. 2002 Feb;16(1):109-16.



Cox G, Mujika I, Tumilty D, Burke L. Acute creatine supplementation and performance during a field test simulating match play in elite female soccer players. Int J Sport Nutr Exerc Metab. 2002 Mar;12(1):33-46.



Dash AK, Mo Y, Pyne A. Solid-state properties of creatine monohydrate. J Pharm Sci. 2002 Mar;91(3):708-18.



Dawson B, Vladich T, Blanksby BA. Effects of 4 weeks of creatine supplementation in junior swimmers on freestyle sprint and swim bench performance. J Strength Cond Res. 2002 Nov;16(4):485-90.



Delecluse C, Diels R, Goris M. Effect of creatine supplementation on intermittent sprint running performance in highly trained athletes. J Strength Cond Res. 2003 Aug;17(3):446-54.



Dempsey RL, Mazzone MF, Meurer LN. Does oral creatine supplementation improve strength? A meta-analysis. J Fam Pract. 2002 Nov;51(11):945-51.



Derave W, Eijnde BO, Hespel P. Creatine supplementation in health and disease: what is the evidence for long-term efficacy? Mol Cell Biochem. 2003 Feb;244(1-2):49-55.



Derave W, Eijnde BO, Verbessem P, Ramaekers M, Van Leemputte M, Richter EA, Hespel P. Combined creatine and protein supplementation in conjunction with resistance training promotes muscle GLUT-4 content and glucose tolerance in humans. J Appl Physiol. 2003 May;94(5):1910-6. Epub 2003 Jan 10.



Derave, Bert O. Eijnde, Patricia Verbessem, Monique Ramaekers, Mark Van Leemputte, Erik A. Richter, and Peter Hespel. Combined creatine and protein supplementation in conjunction with resistance training promotes muscle GLUT-4 content and glucose tolerance in humans. J Appl Physiol, May 2003; 94: 1910 - 1916.



Doherty M, Smith PM, Davison RC, Hughes MG. Caffeine is ergogenic after supplementation of oral creatine monohydrate. Med Sci Sports Exerc. 2002 Nov;34(11):1785-92.



Earnest, Anthony L. Almada and Tedd L. Mitchell. 1997: Effects of Creatine Monohydrate Ingestion on Intermediate Duration Anaerobic Treadmill Running to Exhaustion. The Journal of Strength and Conditioning Research: Vol. 11, No. 4, pp. 234–238.



Eckerson, Joan M., Jeffrey R. Stout, Geri A. Moore, Nancy J. Stone, Kami Nishimura and Kristie Tamura. 2004: Effect of Two and Five Days of Creatine Loading on Anaerobic Working Capacity in Women. The Journal of Strength and Conditioning Research: Vol. 18, No. 1, pp. 168–173.



Eckerson JM, Stout JR, Moore GA, Stone NJ, Nishimura K, Tamura K. Effect of two and five days of creatine loading on anaerobic working capacity in women. J Strength Cond Res. 2004 Feb;18(1):168-73.



Edwards, E. C. Rhodes, D. C. McKenzie and A. N. Belcastro. 2000: The Effect of Creatine Supplementation on Anaerobic Performance in Moderately Active Men. The Journal of Strength and Conditioning Research: Vol. 14, No. 1, pp. 75–79.



Ehlers GG, Ball TE, Liston L. Creatine Kinase Levels are Elevated During 2-A-Day Practices in Collegiate Football Players. J Athl Train. 2002 Jun;37(2):151-156.



Eijnde BO, Lebacq J, Ramaekers M, Hespel P. Effect of muscle creatine content manipulation on contractile properties in mouse muscles. Muscle Nerve. 2004 Mar;29(3):428-35.



Eijnde BO, Van Leemputte M, Goris M, Labarque V, Taes Y, Verbessem P, Vanhees L, Ramaekers M, Vanden Eynde B, Van Schuylenbergh R, Dom R, Richter EA, Hespel P. Effects of creatine supplementation and exercise training on fitness in men 55-75 yr old. J Appl Physiol. 2003 Aug;95(2):818-28. Epub 2003 Mar 28.



Falk, K. A. Heelan, J. P. Thyfault and A. J. Koch. 2003: Effects of Effervescent Creatine, Ribose, and Glutamine Supplementation on Muscular Strength, Muscular Endurance, and Body Composition. The Journal of Strength and Conditioning Research: Vol. 17, No. 4, pp. 810–816.



Farquhar WB, Zambraski EJ. Effects of creatine use on the athlete's kidney. Curr Sports Med Rep. 2002 Apr;1(2):103-6.



Ferreira MS, RD, CSCS. 1999: Creatine Supplementation for Female Athletes: A Call for Research. Strength and Conditioning Journal: Vol. 21, No. 2, pp. 63–64.



Gagnon M, Maguire M, MacDermott M, Bradford A. Effects of creatine loading and depletion on rat skeletal muscle contraction. Clin Exp Pharmacol Physiol. 2002 Oct;29(10):885-90.



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Gotshalk LA, Volek JS, Staron RS, Denegar CR, Hagerman FC, Kraemer WJ. Creatine supplementation improves muscular performance in older men. Med Sci Sports Exerc. 2002 Mar;34(3):537-43.



Gill, Rowan D. Hall and Anthony J. Blazevich. 2004: Creatine Serum Is Not as Effective as Creatine Powder for Improving Cycle Sprint Performance in Competitive Male Team-Sport Athletes. The Journal of Strength and Conditioning Research: Vol. 18, No. 2, pp. 272–275.



Gill ND, Hall RD, Blazevich AJ. Creatine serum is not as effective as creatine powder for improving cycle sprint performance in competitive male team-sport athletes. J Strength Cond Res. 2004 May;18(2):272-5.



Green JM, McLester JR, Smith JE, Mansfield ER. The effects of creatine supplementation on repeated upper- and lower-body Wingate performance. J Strength Cond Res. 2001 Feb;15(1):36-41.



Greenwood M, Kreider RB, Greenwood L, Byars A. Cramping and Injury Incidence in Collegiate Football Players Are Reduced by Creatine Supplementation. J Athl Train. 2003 Sep;38(3):216-219.



Greenwood M, Kreider RB, Melton C, Rasmussen C, Lancaster S, Cantler E, Milnor P, Almada A. Creatine supplementation during college football training does not increase the incidence of cramping or injury. Mol Cell Biochem. 2003 Feb;244(1-2):83-8.



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Jenkins, Kelly and David G. Jenkins. 1998: Effect of Oral Creatine Supplementation on Near-Maximal Strength and Repeated Sets of High-Intensity Bench Press Exercise. The Journal of Strength and Conditioning Research: Vol. 12, No. 2, pp. 109–115.



Jones AM, Carter H, Pringle JS, Campbell IT. Effect of creatine supplementation on oxygen uptake kinetics during submaximal cycle exercise. J Appl Physiol. 2002 Jun;92(6):2571-7.



Kambis KW, Pizzedaz SK. Short-term creatine supplementation improves maximum quadriceps contraction in women. Int J Sport Nutr Exerc Metab. 2003 Mar;13(1):87-96.



Kanemitsu F, Kageoka T, Kira S. Heterogeneity of mitochondrial creatine kinase. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jul 5;806(2):95-100.



Kilduff LP, Pitsiladis YP, Tasker L, Attwood J, Hyslop P, Dailly A, Dickson I, Grant S. Effects of creatine on body composition and strength gains after 4 weeks of resistance training in previously nonresistance-trained humans. Int J Sport Nutr Exerc Metab. 2003 Dec;13(4):504-20.



Kilduff LP, Vidakovic P, Cooney G, Twycross-Lewis R, Amuna P, Parker M, Paul L, Pitsiladis YP. Effects of creatine on isometric bench-press performance in resistance-trained humans. Med Sci Sports Exerc. 2002 Jul;34(7):1176-83.



Kinugasa R, Akima H, Ota A, Ohta A, Sugiura K, Kuno SY. Short-term creatine supplementation does not improve muscle activation or sprint performance in humans. Eur J Appl Physiol. 2004 Mar;91(2-3):230-7. Epub 2003 Oct 22.



Kirksey, Michael H. Stone, Beverly J. Warren, Robert L. Johnson, M. Stone, G. G. Haff, F. E. Williams and C. Proulx. 1999: The Effects of 6 Weeks of Creatine Monohydrate Supplementation on Performance Measures and Body Composition in Collegiate Track and Field Athletes. The Journal of Strength and Conditioning Research: Vol. 13, No. 2, pp. 148–156.



Kleiner, Michael E. Worley and Daniel L. Blessing. 1996: Creatine Kinase Response to Various Protocols of Resistance Exercise. The Journal of Strength and Conditioning Research: Vol. 10, No. 1, pp. 15–19.



Kocak S, Karli U. Effects of high dose oral creatine supplementation on anaerobic capacity of elite wrestlers. J Sports Med Phys Fitness. 2003 Dec;43(4):488-92.



Korzun WJ. Oral creatine supplements lower plasma homocysteine concentrations in humans. Clin Lab Sci. 2004 Spring;17(2):102-6.



Kreider RB. Effects of creatine supplementation on performance and training adaptations. Mol Cell Biochem. 2003 Feb;244(1-2):89-94.



Kreider PhD. 1995: The Effect of Creatine Loading on Muscular Strength and Body Compostion. Strength and Conditioning: Vol. 17, No. 5, pp. 72–73.



Kreider RB, Melton C, Rasmussen CJ, Greenwood M, Lancaster S, Cantler EC, Milnor P, Almada AL. Long-term creatine supplementation does not significantly affect clinical markers of health in athletes. Mol Cell Biochem. 2003 Feb;244(1-2):95-104.



Kurosawa Y, Hamaoka T, Katsumura T, Kuwamori M, Kimura N, Sako T, Chance B. Creatine supplementation enhances anaerobic ATP synthesis during a single 10 sec maximal handgrip exercise. Mol Cell Biochem. 2003 Feb;244(1-2):105-12.



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Larson-Meyer, G. R. Hunter, C. A. Trowbridge, J. C. Turk, J. M. Ernest, S. L. Torman and P. A. Harbin.. 2000: The Effect of Creatine Supplementation on Muscle Strength and Body Composition During Off-Season Training in Female Soccer Players. The Journal of Strength and Conditioning Research: Vol. 14, No. 4, pp. 434–442.



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Roy BD, Bourgeois JM, Mahoney DJ, Tarnopolsky MA. Dietary supplementation with creatine monohydrate prevents corticosteroid-induced attenuation of growth in young rats. Can J Physiol Pharmacol. 2002 Oct;80(10):1008-14.



Sakata Y, Shiraishi S, Otsuka M. Characterization of dehydration behavior of untreated and pulverized creatine monohydrate powders. Colloids Surf B Biointerfaces. 2004 Jun 1;35(3-4):185-91.



Scheff SW, Dhillon HS. Creatine-enhanced diet alters levels of lactate and free fatty acids after experimental brain injury. Neurochem Res. 2004 Feb;29(2):469-79.



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Selsby, Robert A. DiSilvestro and Steven T. Devor. 2004: Mg2+-Creatine Chelate and a Low-Dose Creatine Supplementation Regimen Improve Exercise Performance. The Journal of Strength and Conditioning Research: Vol. 18, No. 2, pp. 311–315.



Snow RJ, Murphy RM. Factors influencing creatine loading into human skeletal muscle. Exerc Sport Sci Rev. 2003 Jul;31(3):154-8.



Speer O, Neukomm LJ, Murphy RM, Zanolla E, Schlattner U, Henry H, Snow RJ, Wallimann T. Creatine transporters: a reappraisal. Mol Cell Biochem. 2004 Jan-Feb;256-257(1-2):407-24.



Stanton and G. A. Abt. 2000: Creatine Monohydrate Use Among Elite Australian Power Lifters. The Journal of Strength and Conditioning Research: Vol. 14, No. 3, pp. 322–327.



Steenge, E. J. Simpson, and P. L. Greenhaff. Protein- and carbohydrate-induced augmentation of whole body creatine retention in humans. J Appl Physiol, Sep 2000; 89: 1165 - 1171.



Stevenson and G. A. Dudley. 2001: Creatine Loading, Resistance Exercise Performance, and Muscle Mechanics. The Journal of Strength and Conditioning Research: Vol. 15, No. 4, pp. 413–419.



Stout, J. M. Eckerson, T. J. Housh and K. T. Ebersole. 1999: The Effects of Creatine Supplementation on Anaerobic Working Capacity. The Journal of Strength and Conditioning Research: Vol. 13, No. 2, pp. 135–138.



Sutherland S. Creatine as a neuroprotector. Drug Discov Today. 2004 Sep 15;9(18):776.



Syrotuik DG, Bell GJ. Acute creatine monohydrate supplementation: a descriptive physiological profile of responders vs. nonresponders. J Strength Cond Res. 2004 Aug;18(3):610-7.



Syrotuik, G. J. Bell, R. Burnham, L. L. Sim, R. A. Calvert and I. M. Maclean. 2000: Absolute and Relative Strength Performance Following Creatine Monohydrate Supplementation Combined With Periodized Resistance Training. The Journal of Strength and Conditioning Research: Vol. 14, No. 2, pp. 182–190.



Syrotuik DG, Game AB, Gillies EM, Bell GJ. Effects of creatine monohydrate supplementation during combined strength and high intensity rowing training on performance. Can J Appl Physiol. 2001 Dec;26(6):527-42.



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Taes YE, Speeckaert M, Bauwens E, De Buyzere MR, Libbrecht J, Lameire NH, Delanghe JR. Effect of dietary creatine on skeletal muscle myosin heavy chain isoform expression in an animal model of uremia. Nephron Exp Nephrol. 2004;96(4):e103-10.



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mr_speedy

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hahaha a long term study is like 10 years +

and considering creatinne has only been freely avaiable on the market since the mid 90s..........
 

hYperTrOphY

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I just showed Joe Yu Yevon King that article, and this is what he said:

Quote:
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Creatine phosphate is actually produced and stored by the kidneys and liver. So.... If the body is receiving an external supply of creatine, it will automatically shut down all production


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Countless studies have shown that creatine does not do this. Creatine is not "produced" in the body, it is synthesized.

Many people confuse the "on/off switch" of creatine to work on the same mechanism as testosterone. Endogenous testosterone production is halted when exogenous testosterone is introduced into the system. But this is due to the negative feedback mechanism which acts hormonally on gonadotropins, which supresses natural testosterone production. This negative feedback system does not exist for creatine.

To make sure we're clear, let me reiderate: Creatine supplementation will not hinder natural creatine synthesis in the body. It is a physiological impossability for it to do so.


Quote:
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This will create a condition, chemical dependency, making creatine a DRUG


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Not at all. In fact, creatine is not located on any Drug Schedule in any state. By comparrison, steroids are a Schedule III drug.

Creatine is not a drug in any way, shape or form. Nor does any government agency recognize it as such.


Quote:
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Later down the line, you'll experience kidney and liver damage. Why? Because the by-product of creatine, creatinine, is similar to uric acid, it is a toxin. When too much builds up, it puts stress on these two organs.



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Again, this is simply not correct. In fact, it has been shown that creatine enhances renal function. And on top of that, creatine is now being used to investigate alternative treatments to spinal cord injuries!
 

hYperTrOphY

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Without Wings said:
Yu Yevon is a nickname, taken from FF.

"Administrator of Hyperplasia Research
Writer for the Journal of Hyperplasia Research"
is what he claims to be...
sounds impressive...
but the Journal of Hyperplasia Research is not a scientific journal

please ppl, when researching a supplement, check the credentials of the person whos advice you are taking.
I know who he is.
He is a scientist and bodybuilder. He almost has his PhD also.

I may also add, that it is irrelevent as to who HE is. More importantly are the people of whom he gets his information. (Refer to resource list above).

Anyway, I dont want to 'debate' any longer. It is up to the individual as to whom they believe. If you dont want to believe this person because the Journal that he writes for (which is absolutely amazing I may add) is not - in your opinion a scientific journal - that is your choice.
 
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hYperTrOphY

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Without Wings said:
ok if you dont wish to debate anylonger, then please dont feel like you have to (i was actually about to split this into a separate thread, "the creatine debate" as it's interesting to see other people's opinions on these subjects because peoples opinions are all different due to different backgrounds and socialisation.
..all this thread is about is allowing people to see both sides to the story - to learn that there's more to taking a supplement then just hearing one good thing about it and taking it. It's about researchign that supplement and ensuring you are getting valid information from valid sources in order to make the best decision FOR YOU possible.
Most people's opinion is irrelevent though. Their opinion has most likely been formed by their next door neighbour's cousin who went to the gym and some big guy told him something.

I guess it's impossible to get rid of all the myths and enlighten all ignorant people, but at least those at ABCbodybuilding will be 'in the know'...
 

hYperTrOphY

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I'm glad that you are so optimistic about the intelligence of the average person. :)

I doubt many people will jump into this debate. My main reason for believeing so is because actual scientific information has been presented, and most people argue only with mere generalisations and uneducated 'opinions'.
 

mr_speedy

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the only supplement i would recommend for a begginer is protein. musashi p40 is my fav.
 

Tommy_69

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take NO supplements with creatine it works well. I personally use BSN Nitrix along with creatine. works great
 

hYperTrOphY

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melbournian said:
And as for Creatine....

The general consensus is that it is safe. If it wasn't safe, it would face the same restrictions as juice, prohormones etc. The Pharmaceutical Goods Administration considers it safe, so I consider it safe. I'm happy with it. I've actually cycled off it for the past two weeks, starting back on it tommorow.
As have I. I'll be loading again as of tomorrow.
 

Cab31

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hYperTrOphY said:
As have I. I'll be loading again as of tomorrow.
can i ask you what exactly you are loading for? Are you an athlete or something?
 

hYperTrOphY

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I'm loading because I have been off creatine for a while unfortunately. Thus, I must load for 5 days before maintaining.
You probably wouldn't class me as an "athlete" I dont think...
I don't compete in any sport, but I do train 7 days a week, so I still class myself as an athlete. I train and diet like an athlete.
 

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