Fabregas has a twin.....?
Pool and Madrid will be interesting. Never ever write off Madrid. Ever. Van Nistelroy back in England will be interesting. Interesting Matchups: Carra and Van Nistelroy, Agger/skertal and Raul, Torres and Cannavarro, Gerrard and Diarra, Robben/Snerijder and Kuyt... And Dudek comes home...
Arsenal and roma should be enjoyable, United and Inter should be great, as should Chelsea and Juve.
Cept for the Pool and Real (cause its just too tight [though Real are have been looking quite good in Europe]), id say all the english teams should go through.
Villa are interesting. They dont exactly have World renowned stars, and have a majority of english players, so they play well as a group. But, in the long run, they would have to get a rich american owner to consolidate their squad, and to get them a bigger stadium and support base. Even if they do well in one season, to break into the "big 4" is a huge ask.
I also think youll find united challenging later in the season......